What is a creatine kinase test?
Definition The creatine kinase test measures the blood levels of certain muscle and brain enzyme proteins. Purpose Creatine kinase (CK or CPK) is an enzyme (a type of protein) found in muscle and brain. Normally, very little CK is found circulating in the blood. Elevated levels indicate damage to either muscle or brain; possibly from a myocardial infarction (heart attack), muscle disease, or stroke. There are three types, or isoforms, of CK: • CK-I, or BB, is produced primarily by brain and smooth muscle. • CK-II, or MB, is produced primarily by heart muscle. • CK-III, or MM, is produced primarily by skeletal muscle. Precautions No special precautions are necessary, except in patients with a bleeding disorder. Description A small amount of blood is drawn and used for laboratory analysis. Preparation Physical activity may cause a rise in CK levels, especially the CK-III fraction. Therefore, patients should not engage in strenuous physical activity the day of the test. The patient should
