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If a patient has undergone a bone marrow transplant, will Navigenics DNA testing be accurate for them?

April 26, 2017accurate bone dna testing marrow Navigenics patient transplant undergone

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If a patient has undergone a bone marrow transplant, will Navigenics DNA testing be accurate for them?

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At this time, Navigenics does not recommend our testing for any individual who has undergone a bone marrow transplant. Studies have demonstrated that DNA from bone a marrow donor can become mixed with the recipients DNA, even in saliva and mouthwash samples. (Endler G, et al. Genetic fingerprinting in mouthwashes of patients after allogeneic bone marrow transplantation. Bone Marrow Transplant 1999; 24: 95–98 and Thiede C, et al. Buccal swabs but not mouthwash samples can be used to obtain pretransplant DNA fingerprints from recipients of allogeneic bone marrow transplants. Bone Marrow Transplant. 2000 Mar;25(5):575-7).