What is rofecoxib?
Rofecoxib (Vioxx) was withdrawn from the U.S. market in 2004. Rofecoxib is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Rofecoxib works by reducing substances that cause inflammation, pain, and fever in the body. Rofecoxib is used to reduce pain, inflammation, and stiffness caused by osteoarthritis, rheumatoid arthritis and certain forms of juvenile rheumatoid arthritis; to manage acute pain in adults; to treat migraines; and to treat menstrual pain. Rofecoxib may also be used for purposes other than those listed in this medication guide.