What is a DNA Profile?
A DNA profile provides a unique, individual identification of an animal. A DNA profile can be used for parentage verification and can resolve any pedigree issues. It also enables for “Clear by Parentage” whereby a pup, which is sired from a clear dam and sire (both previously tested), can be cleared of that disease by verifying the parentage and not requiring disease testing of the puppy. Clear by parentage can reduce costs as parentage testing is much cheaper than disease testing. What benefits would I get from disease testing? The program is about prevention of recurrence, where there is a DNA test for a specific disease known to occur in a breed, responsible breeders should use it, to avoid producing affected offspring. This is not only for the sake of the animals bred, but for the protection of buyers and breeders themselves.
To prepare a DNA Profile, multiple different genetic locations are identified in your dog. If, for example, the first location identified on a dog has genes labeled A and B, that means that the dog inherited an A gene from one parent and a B gene from the other. When the parents are tested, that exact same location will be examined. To continue this hypothetical example, assume the Sire is AJ and the dam is BK. These two parents could have produced the four possible combinations in the table below: A J B| AB | JB K| AK | JK Since AB appears in the above list, there is a match. Just one match is not enough to be certain that this Sire and Dam produced this dog, but each time there is a match, the odds increase that these two are the parents of the dog. Suppose now, that the Sire had tested JM and the Dam BK. It is immediately obvious that neither parent could have contributed an A gene to your dog. The Sire is excluded as a possible parent but the Dam is still included as a possible par
Related Questions
- Ive had the iron profile tests, read them myself and they were within the normal range; do I need to be retested ever again and/or have the DNA genetic test, especially since I feel fine?
- How will my doctor or pharmacist use my personal DNA Prescription Drug Reaction Profile?
- Why DNA profile and bank?
