What are Retin-A (tretinoin) and retinoids?
Currently, the most-studied topical anti-aging treatment is prescription tretinoin (with brands Retin-A, Retin-A Micro, Renova, Avita, or generic). Tretinoin is also called vitamin A acid or retinoic acid; but it is a different chemical from regular vitamin A – one form of which is called retinol. A prescription is required for tretinoin because it produces significant changes in the structure of the skin. Tretinoin was developed many years ago and is often prescribed for acne because it reduces sebum build-up in pores; but a large number of peer-reviewed medical studies done since the early 1980s also show that tretinoin can also improve fine lines, skin texture, and uneven pigmentation. Tretinoin may also improve the appearance of large pores and some scars. It is has been shown conclusively that tretinoin acts to improve collagen in the dermis, thicken the epidermis, and smooth the skin surface. The effects are modest with most people, but a few people achieve significant improvemen
