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• COCKLEBUR (noun) The noun COCKLEBUR has 2 senses: 1. any coarse weed of the genus Xanthium having spiny burrs 2. burdock having heart-shaped leaves found in open woodland, hedgerows and rough grassland of Europe (except extreme N) and Asia Minor; sometimes cultivated for medicinal and culinary use Familiarity information: COCKLEBUR used as a noun is rare.
