How is Apert Syndrome Inherited?
Apert syndrome is an autosomal dominant type of disease. This means that only one copy of the altered gene is needed for the disease to occur. Accordingly, an offspring of a parent with Apert syndrome has a 50% chance of getting the mutations and thus the disease. The Apert condition may also result from spontaneous mutations of the genetic material of newborns whose parents have no history of the disorder in their family. The occurrence of the disease is estimated at 1 in 65,000 to 88,000 newborns.
