What are the symptoms of myeloma?
The first symptom of myeloma is often back pain, sometimes spreading to the ribs, neck or pelvis. Other symptoms may include any of the following: Excessive tiredness and lethargy due to a lack of red blood cells in the blood (anaemia). Kidney problems caused by the paraproteins produced by the myeloma cells. Kidney damage can increase tiredness and anaemia. Repeated colds, coughs and other infections (particularly chest infection) because of a shortage of normal antibodies. Weakening of the bones by the myeloma cells, which may increase the risk of fractures. Loss of appetite, feelings of sickness, constipation, depression and drowsiness caused by too much calcium in the blood (hypercalcaemia). The excess calcium comes from the damaged bones. Unexplained bruising and abnormal bleeding (nosebleeds or bleeding gums) because the number of platelets in your blood has decreased. Pins and needles, numbness, tingling or weakness in the feet or legs. Difficulty passing urine or opening your b
