What Is the Half-Life of Methadone?
The elimination half-life of a medication is the time it takes for the blood levels of the drug to be reduced by half. There may be significant variation from one person to the next. A wide range of elimination half-lives for methadone (8 to 59 hours) have been reported. This means that every 8 to 59 hours, the level of methadone in your blood will drop by 50 percent of the previous level.
