WHAT IS THE ROLE OF MAO IN DEPRESSION?
The neurotransmitters known as serotonin and noreprinepherine are apparently needed for normal brain functioning. Most researchers believe that reduced levels of these substances lead to an inability of the brain to conduct neural impulses and function normally. Depression can be the result. MAO is present to metabolize these neurotransmitters and keep them from becoming too predominant; this could lead to too much neural firing and “manic” behavior. However, the MAO may do its job too well, thus leaving the brain with a deficiency of serotonin or noreprinepherine. Low energy and depression can result.
