Sometimes physicians do not make a diagnosis of necrotizing fasciitis until several days after a case is admitted to the hospital – is it too late to start prophylactic antibiotics at that time?
It is sometimes difficult to make a diagnosis of necrotizing fasciitis, and both surgery and a definitive diagnosis may be delayed for several days. Fortunately, these cases are usually representative of less severe disease. Since most illness in household contacts occurs in the first two weeks after exposure, prophylaxis should be initiated if a diagnosis is made within the first 10 days.
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