Can I get copies of supporting documents for interim toxicity constants which are coded “P” in the SL Table?
EPA’s OSRTI sponsored the development of provisional peer-reviewed toxicity values (PPRTVs) for contaminants without IRIS. PPRTVs (coded “P” on the SL Table) are developed for use on Superfund or hazardous waste sites. In March 2004, OSRTI posted the PPRTV database on the internet on a trial basis and solicited feedback from stakeholders. Concerns were raised about the potential for misuse of these values and for misunderstanding of what these values represent. Consequently, EPA has removed the PPRTVs from the Internet. We are currently investigating other options for distributing this information. If you have a critical issue during this interim period, contact Dave Crawford via email at crawford.dave@epa.gov. • For manganese, IRIS shows an oral RfD of 0.14 mg/kg-day, but the SL Table uses 0.024 mg/kg-day. Why? The IRIS RfD includes manganese from all sources, including diet. The explanatory text in IRIS recommends using a modifying factor of 3 when calculating risks associated with n
EPA’s OSRTI sponsored the development of provisional peer-reviewed toxicity values (PPRTVs) for contaminants without IRIS. PPRTVs (coded “P” on the SL Table) are developed for use on Superfund or hazardous waste sites. In March 2004, OSRTI posted the PPRTV database on the internet on a trial basis and solicited feedback from stakeholders. Concerns were raised about the potential for misuse of these values and for misunderstanding of what these values represent. Consequently, EPA has removed the PPRTVs from the Internet. We are currently investigating other options for distributing this information. If you have a critical issue during this interim period, contact Dave Crawford via email at crawford.dave@epa.gov.
