What is a Reference Sequence?
The NCBI Reference Sequence project provides sequence data and related information for numerous organisms and provides a baseline for medical, functional, and comparative studies. Whereas GenBank is an archival repository of all sequences, the RefSeq database is a non-redundant set of reference standards that includes chromosomes, complete genomic molecules (organelle genomes, viruses, plasmids), intermediate assembled genomic contigs, curated genomic regions, mRNAs, RNAs, and proteins. RefSeq records are provided using several processes: • Entrez Genomes processing provides genomic, RNA, and protein records for numerous organisms as data becomes available. This pipeline provides all of the bacterial, viral, organelle, and plasmid RefSeq records and also provides some of the records for larger genomes including plants and fungi.
The NCBI Reference Sequence project provides sequence data and related information for numerous organisms and provides a baseline for medical, functional, and comparative studies. Whereas GenBank is an archival repository of all sequences, the RefSeq database is a non-redundant set of reference standards that includes chromosomes, complete genomic molecules (organelle genomes, viruses, plasmids), intermediate assembled genomic contigs, curated genomic regions, mRNAs, RNAs, and proteins. RefSeq records are provided using several processes: • Entrez Genomes processing provides genomic, RNA, and protein records for numerous organisms as data becomes available. This pipeline provides all of the bacterial, viral, organelle, and plasmid RefSeq records and also provides some of the records for larger genomes including plants and fungi. • The NCBI Annotation process, an automated computational method, provides intermediate assembled contigs and some records representing potential transcripts a
Related Questions
- What is the reference database for the ADT (e.g., source and version for sequence, Minor Allele Frequency [MAF], validation)?
- My VP1.5 sequence read matches the reference but my XL39 shows no BLAST similarity to anything?
- How do I find a Reference Sequence (RefSeq) accession number for my gene of interest?
